Zenless Zone Zero New Shiyu Defense Lineup Recommendation

Kerry
01/16/2026

Since a new cycle of Shiyu Defense has been released at Jan.9. It have to say that this time the pressure is really intense for Proxies. So here we are to recommend you about the best lineup of this Shiyu Defense.

The Shiyu Defense has changed to a new form, in the past it has 7 floors and each floor with 2 levels. But now it change to 5 floors and the final floor become 3 levels that require Proxies to conquer them with different lineups.

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Floor 1 to 4 lineup

Floor 1 to 4 are relatively easier to Floor 5, so here we will integrated Floor 1 to 4 together.

 Floor 1 to 4
Bonus BuffsAgent CRIT DMG increases by 15%.
While in Ether Veil, Agent ATK increases by 25%, and attacks ignore 10% of enemy’s DEF.
Team 1
Ye Shunguang

Dialyn

Zhao
Team 2
Yidhari

Lycaon

Lucia

Since Floor 1 to 4 share the same weakness. Level 1 are Fire and Physical weakness and Level 2 are Ice and Ether weak. Proxies can use just one setup to conquer Floor 1 to 4.

Floor 5 Lineup

It becomes more difficult in Floor 5 compare to the previous Floors. So we introduce it room by room. And the Rules of earning Points change from wiping out the opponents within the specified time to specific the point into different times with different multiplier bonuses.

Room 1

Room 1 Proxies need to face the boss with Ether and Physical Weakness and Fire RES. We suggest Proxies to use agents who can activate the Ether Veil to conquer it, Like Zhao or Lucia.

Agent CRIT DMG increases by 15%.
While in Ether Veil, Agent ATK increases by 25%, and attacks ignore 10% of enemy’s DEF.

Ye Shunguang

Dialyn

Zhao

Yixuan

Dialyn

Lucia

Alice

Yuzuha

Lucia

Room 2

In Room 2 we’ve got Ether and Ice RES, which mean it is hard to use Yixuan and Miyabi in this room. However this room’s buff encourage Proxies to against with Anomaly teams, so Alice or Yanagi is recommended here.

Agent Electric DMG and Fire DMG increase by 30%, Anomaly Proficiency increases by 60.
Agents start with 40 additional Energy, Attribute Anomaly DMG increases by 20%.

Alice

Astra Yao

Yuzuha

Soldier 0 Anby

Trigger

Orphie

Yanagi

Burnice

Yuzuha

Room 3

In Room 3 There is only one Ether Weakness and one Electric RES. So the lineup choices are multiple. And the buffs of this room encourage Proxies to use different lineup to conquer, like Yixuan or Yidhari.

Agent Sheer DMG increases by 10%, CRlT DMG increases by 25%.
When an Agent’s Ultimate hits enemies, ignores 10% of their AII-DMG RES.

Yixuan

Ju Fufu

Lucia

Yidhari

Lycaon

Lucia

Banyue

Ju Fufu

Lucia

These are all the lineups of this Shiyu Defense. This time with new mechanics makes the Shiyu Defense much more harder than before. Therefore a powerful Agent set is very important for Proxies and we recommend you to top up on Enjoygm to get Morochrome for Agents.

Conclusion

Here are the Lineup Guide of the Shiyu Defense at the moment, the new mechanic and scoring method make it harder this time. But with this lineup guide, Proxies will be able to conquer it easier.

Writer
Kerry
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